Caspofungin acetate ( L-743872;L-743873;MK-0991 )

Catalog No. M12707 CAS No. 179463-17-3

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Product Name

Caspofungin acetate
Note

Research use only, not for human use.
Brief Description

A lipopeptide antifungal agent that works by inhibiting the enzyme 1,3-beta-glucan synthase and thereby disturbing the integrity of the fungal cell wall.
Description

A lipopeptide antifungal agent that works by inhibiting the enzyme 1,3-beta-glucan synthase and thereby disturbing the integrity of the fungal cell wall.Fungal Infection Approved
Synonyms

L-743872;L-743873;MK-0991
Pathway

Microbiology/Virology
Target

Fungal
Recptor

1,3-beta-D-glucansynthesis
Research Area

Infection
Indication

Fungal Infection

CAS Number

179463-17-3
Formula Weight

1213.42
Molecular Formula

C56H96N10O19
Purity

>98% (HPLC)
Solubility

H2O: ≥ 100 mg/mL
SMILES

CC(O)=O.CC(O)=O.CCC(C)CC(C)CCCCCCCCC(=O)NC1CC(O)C(NCCN)NC(=O)C2C(O)CCN2C(=O)C(NC(=O)C(NC(=O)C2CC(O)CN2C(=O)C(NC1=O)C(C)O)C(O)C(O)C1=CC=C(O)C=C1)C(O)CCN
Chemical Name

Pneumocandin B0, 1-[(4R,5S)-5-[(2-aminoethyl)amino]-N2-[(10R,12S)-10,12-dimethyl-1-oxotetradecyl]-4-hydroxy-L-ornithine]-5-[(3R)-3-hydroxy-L-ornithine]-, acetate (1:2)

1. Campbell JA, et al. Biochem J. 1997 Sep 15;326 ( Pt 3):929-39.
2. Mio T, et al. J Bacteriol. 1997 Jul;179(13):4096-105.

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